p107 rabbit pAb
Produktgrößen
50UL
£ POA
ES7012-50UL
100UL
£ POA
ES7012-100UL
Über dieses Produkt
- SKU:
- ES7012
- Zusätzliche Namen:
- RBL1; Retinoblastoma-like protein 1; 107 kDa retinoblastoma-associated protein; p107; pRb1
- Anwendung:
- Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation; as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen; with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition; both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein; it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms hav
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RBL1. AA range:335-384
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
