Bax rabbit pAb
Produktgrößen
50UL
£ POA
ES6947-50UL
100UL
£ POA
ES6947-100UL
Über dieses Produkt
- SKU:
- ES6947
- Anwendung:
- Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by BAX (BCL2 associated X; apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2; and functions as an apoptotic activator. This protein is reported to interact with; and increase the opening of; the mitochondrial voltage-dependent anion channel (VDAC); which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants; which encode different isoforms; have been reported for BAX.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human BAX. AA range:80-129
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
