TOK-1 rabbit pAb
Produktgrößen
50UL
£ POA
ES6850-50UL
100UL
£ POA
ES6850-100UL
Über dieses Produkt
- SKU:
- ES6850
- Zusätzliche Namen:
- BCCIP; TOK1; BRCA2 and CDKN1A-interacting protein; P21- and CDK-associated protein 1; Protein TOK-1
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain; suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression; and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation; double-strand break-induced homologous recombination; and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- Synthesized peptide derived from TOK-1 . at AA range: 60-140
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
