SNAT2 rabbit pAb
Produktgrößen
50UL
£ POA
ES6652-50UL
100UL
£ POA
ES6652-100UL
Über dieses Produkt
- SKU:
- ES6652
- Zusätzliche Namen:
- SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino a
- Anwendung:
- Western Blot, ELISA, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- enzyme regulation:Inhibited by N-methyl-D-glucamine and probably choline.;function:Functions as a sodium-dependent amino acid transporter. Mediates the saturable; pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.;induction:Up-regulated upon hypertonic conditions and amino acid deprivation.;miscellaneous:Depletion of SCL38A2 by siRNA prevents the recovery of cells from hypertonic stress.;PTM:Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.;similarity:Belongs to the amino acid/polyamine transporter 2 family.;subcellular location:Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons; it is also detected at the axonal shaft but excluded from the nerve terminal.;tissue specificity:Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SLC38A2. AA range:151-200
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
