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Antikörper

Pim-1 rabbit pAb

Produktgrößen
50UL
£ POA
ES6589-50UL
100UL
£ POA
ES6589-100UL
Über dieses Produkt
SKU:
ES6589
Zusätzliche Namen:
PIM1; Serine/threonine-protein kinase pim-1
Anwendung:
Western Blot, Immunohistochemistry
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family; and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines; and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells; contributing to both cell proliferation and survival; and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons; the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805; 1825810).[provided by RefSeq; Aug 2011];
Immunogen:
The antiserum was produced against synthesized peptide derived from human Pim-1. AA range:281-330
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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