c-Myc (phospho Ser373) rabbit pAb
Produktgrößen
50UL
£ POA
ES6305-50UL
100UL
£ POA
ES6305-100UL
Über dieses Produkt
- SKU:
- ES6305
- Zusätzliche Namen:
- MYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
- Anwendung:
- Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a multifunctional; nuclear phosphoprotein that plays a role in cell cycle progression; apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations; overexpression; rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors; leukemias and lymphomas; including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream; in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas; suggesting its importance in the normal function of this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Myc around the phosphorylation site of Ser373. AA range:340-389
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
