MDM2 rabbit pAb
Produktgrößen
50UL
£ POA
ES6212-50UL
100UL
£ POA
ES6212-100UL
Über dieses Produkt
- SKU:
- ES6212
- Zusätzliche Namen:
- MDM2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2
- Anwendung:
- Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins; such as p53; for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants; many of which may be expressed only in tumor cells. [provided by RefSeq; Jun 2013];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MDM2. AA range:151-200
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
