GluR-δ2 rabbit pAb
Produktgrößen
50UL
£ POA
ES5640-50UL
100UL
£ POA
ES5640-100UL
Über dieses Produkt
- SKU:
- ES5640
- Zusätzliche Namen:
- GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit
- Anwendung:
- Western Blot, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog; associated with the phenotype named 'lurcher'; in the heterozygous state leads to ataxia resulting from selective; cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
