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Antikörper

Ksr2 rabbit pAb

Produktgrößen
50UL
£ POA
ES5584-50UL
100UL
£ POA
ES5584-100UL
Über dieses Produkt
SKU:
ES5584
Zusätzliche Namen:
KSR2; Kinase suppressor of Ras 2; hKSR2
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
domain:The protein kinase domain is predicted to be catalytically inactive.;function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK; JNK and NF-kappa-B pathways; inhibiting MAP3K3-mediated interleukin-8 production.;PTM:Phosphorylated on Ser-474 by MARK3.;similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.;similarity:Contains 1 phorbol-ester/DAG-type zinc finger.;similarity:Contains 1 protein kinase domain.;subunit:Interacts with MAP2K1; MAP3K8; MAPK; RAS and RAF.;tissue specificity:Mainly expressed in brain and kidney.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720
Isotyp:
IgG
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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