Sck rabbit pAb
Produktgrößen
50UL
£ POA
ES5437-50UL
100UL
£ POA
ES5437-100UL
Über dieses Produkt
- SKU:
- ES5437
- Zusätzliche Namen:
- SHC2; SCK; SHCB; SHC-transforming protein 2; Protein Sck; SHC-transforming protein B; Src homology 2 domain-containing-transforming protein C2; SH2 domain protein C2
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- domain:The PID domain mediates binding to the TrkA receptor.;function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.;miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors; in opposite to PubMed:12006576.;PTM:Phosphorylated on tyrosines by the Trk receptors.;similarity:Contains 1 PID domain.;similarity:Contains 1 SH2 domain.;subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated; binds to GRB2.;tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SHC2. AA range:261-310
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
