JMJD2B rabbit pAb
Produktgrößen
50UL
£ POA
ES5294-50UL
100UL
£ POA
ES5294-100UL
Über dieses Produkt
- SKU:
- ES5294
- Zusätzliche Namen:
- KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
- Anwendung:
- Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- cofactor:Binds 1 Fe(2+) ion per subunit.;domain:The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.;function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3; thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4'; H3 'Lys-27'; H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9'; with a weaker activity than KDM4A; KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.;similarity:Belongs to the JHDM3 histone demethylase family.;similarity:Contains 1 JmjC domain.;similarity:Contains 1 JmjN domain.;similarity:Contains 2 PHD-type zinc fingers.;similarity:Contains 2 Tudor domains.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human KDM4B. AA range:351-400
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
