NDR2 rabbit pAb
Produktgrößen
50UL
£ POA
ES5289-50UL
100UL
£ POA
ES5289-100UL
Über dieses Produkt
- SKU:
- ES5289
- Zusätzliche Namen:
- STK38L; KIAA0965; NDR2; Serine/threonine-protein kinase 38-like; NDR2 protein kinase; Nuclear Dbf2-related kinase 2
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;cofactor:Magnesium.;enzyme regulation:Activated by binding of S100B which releases autoinhibitory N-lobe interactions; enabling ATP to bind and the autophosphorylation of Ser-282. Thr-442 then undergoes calcium-dependent phosphorylation by an upstream kinase. Interactions between phosphorylated Thr-442 and the N-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of MOB1/MOBKL1A and MOB2/HCCA2 to the N-terminal of STK38L.;function:Involved in the regulation of structural processes in differentiating and mature neuronal cells.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.;similarity:Contains 1 AGC-kinase C-terminal domain.;similarity:Contains 1 protein kinase domain.;subcellular location:Associated with the actin cytoskeleton.;subunit:Homodimeric S100B binds two molecules of STK38L (By similarity). Interacts with MOB1 and MOB2.;tissue specificity:Ubiquitously expressed with highest levels observed in the thymus.;
- Immunogen:
- Synthesized peptide derived from NDR2 . at AA range: 380-460
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
