ZNRF2 rabbit pAb
Produktgrößen
50UL
£ POA
ES5237-50UL
100UL
£ POA
ES5237-100UL
Über dieses Produkt
- SKU:
- ES5237
- Zusätzliche Namen:
- ZNRF2; RNF202; E3 ubiquitin-protein ligase ZNRF2; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2
- Anwendung:
- Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- domain:The RING-type zinc finger domain is required for E3 ligase activity.;function:May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.;pathway:Protein modification; protein ubiquitination.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Contains 1 RING-type zinc finger.;subcellular location:Present in presynaptic plasma membranes in neurons.;subunit:Interacts with UBE2N.;tissue specificity:Highly expressed in the brain; with higher expression during development than in adult. Expressed also in mammary glands; testis; colon and kidney.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ZNRF2. AA range:161-210
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
