Cleaved-Factor XIIIa (G39) rabbit pAb
Produktgrößen
50UL
£ POA
ES5191-50UL
100UL
£ POA
ES5191-100UL
Über dieses Produkt
- SKU:
- ES5191
- Zusätzliche Namen:
- F13A1; F13A; Coagulation factor XIII A chain; Coagulation factor XIIIa; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function; and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits; which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion; the plasma factor XIII dissociates its B subunits and yields the same active enzyme; factor XIIIa; as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules; thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor; or
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FA13A. AA range:20-69
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
