Sgo2 rabbit pAb
Produktgrößen
50UL
£ POA
ES4904-50UL
100UL
£ POA
ES4904-100UL
Über dieses Produkt
- SKU:
- ES4904
- Zusätzliche Namen:
- SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
- Anwendung:
- Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:During meiosis; protects centromeric cohesion complexes until metaphase II/anaphase II transition; preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres; thus leading to cohesin dephosphorylation.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;sequence caution:Contaminating sequence. Potential poly-A sequence.;similarity:Belongs to the shugoshin family.;subcellular location:In Hela cells; localizes at centromeres throughout prophase until metaphase and disappears at anaphase.;subunit:Directly interacts with PPP2CA.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
