SIK1 rabbit pAb
Produktgrößen
50UL
£ POA
ES4895-50UL
100UL
£ POA
ES4895-100UL
Über dieses Produkt
- SKU:
- ES4895
- Zusätzliche Namen:
- SIK1; SIK; SNF1LK; Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;cofactor:Magnesium.;enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.;function:Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators; CRTC1-3.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.;similarity:Contains 1 protein kinase domain.;similarity:Contains 1 UBA domain.;subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.;subunit:Binds to and is activated by YWHAZ when phosphorylated on Thr-182.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SIK. AA range:148-197
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
