Csk (phospho Ser364) rabbit pAb
Produktgrößen
50UL
£ POA
ES4854-50UL
100UL
£ POA
ES4854-100UL
Über dieses Produkt
- SKU:
- ES4854
- Zusätzliche Namen:
- CSK; Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.;function:Specifically phosphorylates 'Tyr-504' on LCK; which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.;PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.;similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.;similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.;similarity:Contains 1 protein kinase domain.;similarity:Contains 1 SH2 domain.;similarity:Contains 1 SH3 domain.;subcellular location:Mainly cytoplasmic; also present in lipid rafts.;subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1; PAG1; LIME1 and TGFB1I1.;tissue specificity:Expressed in lung and macrophages.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Csk around the phosphorylation site of Ser364. AA range:330-379
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
