MRP2 rabbit pAb
Produktgrößen
50UL
£ POA
ES4715-50UL
100UL
£ POA
ES4715-100UL
Über dieses Produkt
- SKU:
- ES4715
- Zusätzliche Namen:
- ABCC2; CMOAT; CMOAT1; CMRP; MRP2; Canalicular multispecific organic anion transporter 1; ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore; this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS); an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ABCC2. AA range:991-1040
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
