JDP2 rabbit pAb
Produktgrößen
50UL
£ POA
ES4705-50UL
100UL
£ POA
ES4705-100UL
Über dieses Produkt
- SKU:
- ES4705
- Zusätzliche Namen:
- JDP2; Jun dimerization protein 2
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis; cell differentiation; tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.;PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as; UV irradiation; oxidatives stress and anisomycin treatments.;similarity:Belongs to the bZIP family. ATF subfamily.;similarity:Contains 1 bZIP domain.;subunit:Forms homodimer or heterodimer with JUN; JUNB; JUND; CEBPG and ATF2 thereby inhibiting transactivation by JUN; ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human JDP2. AA range:114-163
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
