CRMP-3 rabbit pAb
Produktgrößen
50UL
£ POA
ES4508-50UL
100UL
£ POA
ES4508-100UL
Über dieses Produkt
- SKU:
- ES4508
- Zusätzliche Namen:
- DPYSL4; CRMP3; ULIP4; Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- disease:Antibodies against post-translationally modified DPYSL4; also called anti-CV2 autoantibodies; are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis; but attributed to remote effects of the cancer.;function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance; neuronal growth cone collapse and cell migration.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.;subunit:Homotetramer; and heterotetramer with CRMP1; DPYSL2; DPYSL3 or DPYSL5. Interacts with PLEXA1.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
