GRIP-1 (phospho Ser736) rabbit pAb
Produktgrößen
50UL
£ POA
ES4485-50UL
100UL
£ POA
ES4485-100UL
Über dieses Produkt
- SKU:
- ES4485
- Zusätzliche Namen:
- NCOA2; BHLHE75; TIF2; Nuclear receptor coactivator 2; NCoA-2; Class E basic helix-loop-helix protein 75; bHLHe75; Transcriptional intermediary factor 2; hTIF2
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors; including steroid; thyroid; retinoid; and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors; which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers; including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia; the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia; and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Mar 2016];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NCoA2 around the phosphorylation site of Ser736. AA range:702-751
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
