CD101 rabbit pAb
Produktgrößen
50UL
£ POA
ES4330-50UL
100UL
£ POA
ES4330-100UL
Über dieses Produkt
- SKU:
- ES4330
- Zusätzliche Namen:
- CD101; EWI101; IGSF2; V7; Immunoglobulin superfamily member 2; IgSF2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.;PTM:N-glycosylated.;similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains.;tissue specificity:Expressed in lung; thymus and small intestine. Detected in cutaneous dendritic cells; activated T-cells; monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells; the CD4(+) CD56(+) blastic tumor cells; as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human CD101. AA range:731-780
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
