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Antikörper

CD42d rabbit pAb

Produktgrößen
50UL
£ POA
ES4317-50UL
100UL
£ POA
ES4317-100UL
Über dieses Produkt
SKU:
ES4317
Zusätzliche Namen:
GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation; a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains; an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720); that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA; GP1BB; and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200); a bleeding disorder (review by Lopez et al.; 1998 [PubMed 9616133]).[supplied by OMIM; Nov 2010];
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human GP5. AA range:331-380
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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