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Antikörper

ZNF384 rabbit pAb

Produktgrößen
50UL
£ POA
ES4261-50UL
100UL
£ POA
ES4261-100UL
Über dieses Produkt
SKU:
ES4261
Zusätzliche Namen:
ZNF384; CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
zinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein; which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1; MMP3; MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene; EWSR1 on chromosome 22; or with the TAF15 gene on chromosome 17; or with the TCF3 (E2A) gene on chromosome 19; have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq; Apr 2011];
Immunogen:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50
Isotyp:
IgG
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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