CD148 rabbit pAb
Produktgrößen
50UL
£ POA
ES4130-50UL
100UL
£ POA
ES4130-100UL
Über dieses Produkt
- SKU:
- ES4130
- Zusätzliche Namen:
- PTPRJ; DEP1; Receptor-type tyrosine-protein phosphatase eta; Protein-tyrosine phosphatase eta; R-PTP-eta; Density-enhanced phosphatase 1; DEP-1; HPTP eta; Protein-tyrosine phosphatase receptor type J; R-PTP-J; CD148
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes; including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats; a single transmembrane region; and a single intracytoplasmic catalytic domain; and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages; and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor; and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human PTPRJ. AA range:861-910
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
