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Antikörper

MCM7 rabbit pAb

Produktgrößen
50UL
£ POA
ES4101-50UL
100UL
£ POA
ES4101-100UL
Über dieses Produkt
SKU:
ES4101
Zusätzliche Namen:
MCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 4 and 6 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase; CDK4; is found to associate with this protein; and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human MCM7. AA range:491-540
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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