TRAF2 rabbit pAb
Produktgrößen
50UL
£ POA
ES3634-50UL
100UL
£ POA
ES3634-100UL
Über dieses Produkt
- SKU:
- ES3634
- Zusätzliche Namen:
- TRAF2; TRAP3; TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- TNF receptor associated factor 2(TRAF2) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with; and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors; and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs); and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD; a TNF receptor associated apoptotic signal transducer; ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1; an apoptosis inhibitor possessing ubiquitin ligase activity; can unbiquitinate and induce the degradation of this pro
- Immunogen:
- Synthesized peptide derived from the Internal region of human TRAF2.
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse, Bovine
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
