TNF-IP 8 rabbit pAb
Produktgrößen
50UL
£ POA
ES3621-50UL
100UL
£ POA
ES3621-100UL
Über dieses Produkt
- SKU:
- ES3621
- Zusätzliche Namen:
- TNFAIP8; Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- developmental stage:Expressed at high levels in the fetal liver; lung and kidney.;function:Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8; subsequently resulting in inhibition of BID cleavage and caspase-3 activation.;induction:By nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB.;similarity:Belongs to the TNFAIP8 family.;tissue specificity:Expressed at high levels in the spleen; lymph node; thymus; thyroid; bone marrow and placenta. Expressed at high levels both in various tumor tissues; unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord; ovary; lung; adrenal glands; heart; brain; testis and skeletal muscle.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TFIP8. AA range:31-80
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
