Separase rabbit pAb
Produktgrößen
50UL
£ POA
ES3423-50UL
100UL
£ POA
ES3423-100UL
Über dieses Produkt
- SKU:
- ES3423
- Zusätzliche Namen:
- ESPL1; ESP1; KIAA0165; Separin; Caspase-like protein ESPL1; Extra spindle poles-like 1 protein; Separase
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates; sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1; or separase; which initiates the final separation of sister chromatids (Sun et al.; 2009 [PubMed 19345191]).[supplied by OMIM; Nov 2010];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SEPARASE. AA range:767-816
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
