Rag A/B rabbit pAb
Produktgrößen
50UL
£ POA
ES3318-50UL
100UL
£ POA
ES3318-100UL
Über dieses Produkt
- SKU:
- ES3318
- Zusätzliche Namen:
- RRAGA; Ras-related GTP-binding protein A; Rag A; RagA; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1; RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K; an inhibitor of TNF-alpha functions; thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.;similarity:Belongs to the GTR/RAG GTP-binding protein family.;subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus; depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.;subunit:Can occur as a homodimer; or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein.;tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle; heart; and brain.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
