PSK-H1 rabbit pAb
Produktgrößen
50UL
£ POA
ES3269-50UL
100UL
£ POA
ES3269-100UL
Über dieses Produkt
- SKU:
- ES3269
- Zusätzliche Namen:
- PSKH1; Serine/threonine-protein kinase H1; Protein serine kinase H1; PSK-H1
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;enzyme regulation:Activity depends on Ca(2+) concentration.;function:May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.;PTM:Autophosphorylated on serine residues.;PTM:Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur.;PTM:Palmitoylated.;similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.;similarity:Contains 1 protein kinase domain.;subcellular location:Localized in the Brefeldin A-sensitive Golgi compartment; at centrosomes; in the nucleus with a somewhat speckle-like presence; membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM); and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes.;subunit:Homodimer.;tissue specificity:Expressed in all tissues and cell lines tested with the highest level of abundance in testis.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human KPSH1. AA range:261-310
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
