p18 rabbit pAb
Produktgrößen
50UL
£ POA
ES3099-50UL
100UL
£ POA
ES3099-100UL
Über dieses Produkt
- SKU:
- ES3099
- Zusätzliche Namen:
- CDKN2C; CDKN6; Cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6; and prevent the activation of the CDK kinases; thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis; as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene; which encode an identical protein; have been reported. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
