p15 rabbit pAb
Produktgrößen
50UL
£ POA
ES3097-50UL
100UL
£ POA
ES3097-100UL
Über dieses Produkt
- SKU:
- ES3097
- Zusätzliche Namen:
- CDKN2B; MTS2; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor; which forms a complex with CDK4 or CDK6; and prevents the activation of the CDK kinases; thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta; which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene; which encode distinct proteins; have been reported. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p15 INK. AA range:89-138
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody