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Antikörper

MMP-2 rabbit pAb

Produktgrößen
50UL
£ POA
ES2806-50UL
100UL
£ POA
ES2806-100UL
Über dieses Produkt
SKU:
ES2806
Zusätzliche Namen:
MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family; that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A; type IV collagenase; that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members; activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases; or; intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system; endometrial menstrual breakdown; regulation of vascularization; and metastasis. Mutations in this gene have been associated with Win
Immunogen:
The antiserum was produced against synthesized peptide derived from human MMP-2. AA range:611-660
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat, Non-human Primate
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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