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Antikörper

Midline-1 rabbit pAb

Produktgrößen
50UL
£ POA
ES2789-50UL
100UL
£ POA
ES2789-100UL
Über dieses Produkt
SKU:
ES2789
Zusätzliche Namen:
MID1; FXY; RNF59; TRIM18; XPRF; Midline-1; Midin; Midline 1 RING finger protein; Putative transcription factor XPRF; RING finger protein 59; Tripartite motif-containing protein 18
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
midline 1(MID1) Homo sapiens The protein encoded by this gene is a member of the tripartite motif (TRIM) family; also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains; a RING; a B-box type 1 and a B-box type 2; and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome; which is characterized by midline abnormalities such as cleft lip; laryngeal cleft; heart defects; hypospadias; and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however; t
Immunogen:
The antiserum was produced against synthesized peptide derived from human TRI18. AA range:71-120
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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