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Antikörper

MGMT rabbit pAb

Produktgrößen
50UL
£ POA
ES2788-50UL
100UL
£ POA
ES2788-100UL
Über dieses Produkt
SKU:
ES2788
Zusätzliche Namen:
MGMT; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Alkylating agents are potent carcinogens that can result in cell death; mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule; which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types; including colorectal cancer; lung cancer; lymphoma and glioblastoma. [provided by RefSeq; Sep 2015];
Immunogen:
The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
Isotyp:
IgG
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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