JMY rabbit pAb
Produktgrößen
50UL
£ POA
ES2661-50UL
100UL
£ POA
ES2661-100UL
Über dieses Produkt
- SKU:
- ES2661
- Zusätzliche Namen:
- JMY; Junction-mediating and -regulatory protein
- Anwendung:
- Western Blot, ELISA, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis; suggesting an important role in p53/TP53 stress response such as DNA damage.;induction:By E2F.;PTM:Ubiquitinated by MDM2; leading to its subsequent degradation by the proteasome. In case of DNA damage; the interaction with MDM2 is altered; preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.;similarity:Contains 1 WH2 domain.;subunit:Interacts with p300/EP300; the complex being recruited to activated p53/TP53. Interacts with TTC5.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human JMY. AA range:931-980
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
