HURP rabbit pAb
Produktgrößen
50UL
£ POA
ES2586-50UL
100UL
£ POA
ES2586-100UL
Über dieses Produkt
- SKU:
- ES2586
- Zusätzliche Namen:
- DLGAP5; DLG7; KIAA0008; Disks large-associated protein 5; DAP-5; Discs large homolog 7; Disks large-associated protein DLG7; Hepatoma up-regulated protein; HURP
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- developmental stage:Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells.;function:Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.;PTM:Ubiquitinated; leading to its degradation.;similarity:Belongs to the SAPAP family.;subcellular location:Localizes to the spindle poles in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.;subunit:Interacts with CDC2. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1-CUL1-F-box) protein complex in a CDC2/Cyclin B-phosphorylation dependent manner. Interacts with CDH1.;tissue specificity:Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow; testis; colon; and placenta.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DLGAP5. AA range:791-840
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
