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Antikörper

Fibulin-5 rabbit pAb

Produktgrößen
50UL
£ POA
ES2344-50UL
100UL
£ POA
ES2344-100UL
Über dieses Produkt
SKU:
ES2344
Zusätzliche Namen:
FBLN5; DANCE; Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a secreted; extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However; its expression is reinduced in balloon-injured vessels and atherosclerotic lesions; notably in intimal vascular smooth muscle cells and endothelial cells. Therefore; the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa; autosomal recessive cutis laxa type I (CL type I); and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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