Factor VIII rabbit pAb
Produktgrößen
50UL
£ POA
ES2314-50UL
100UL
£ POA
ES2314-100UL
Über dieses Produkt
- SKU:
- ES2314
- Zusätzliche Namen:
- F8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes coagulation factor VIII; which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which; in the presence of Ca+2 and phospholipids; converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein; isoform a; which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein; isoform b; which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A; a common recessive X-linked coagulation disorder. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Factor VIII. AA range:2161-2210
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
