E2F-4/5 rabbit pAb
Produktgrößen
50UL
£ POA
ES2213-50UL
100UL
£ POA
ES2213-100UL
Über dieses Produkt
- SKU:
- ES2213
- Zusätzliche Namen:
- E2F4; Transcription factor E2F4; E2F-4; E2F5; Transcription factor E2F5; E2F-5
- Anwendung:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain; a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP); a transactivation domain enriched in acidic amino acids; and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB; p107 and p130; but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human E2F4. AA range:51-100
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat, Non-human Primate
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
