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Antikörper

Cyclin A1 rabbit pAb

Produktgrößen
50UL
£ POA
ES2079-50UL
100UL
£ POA
ES2079-100UL
Über dieses Produkt
SKU:
ES2079
Zusätzliche Namen:
CCNA1; Cyclin-A1
Anwendung:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene belongs to the highly conserved cyclin family; whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain; as well as in several leukemic cell lines; and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases; which give two distinct kinase activities; one appearing in S phase; the other in G2; and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators; such as Rb family proteins; transcription factor E2F-1; and the p21 family proteins. Multi
Immunogen:
The antiserum was produced against synthesized peptide derived from human Cyclin A1. AA range:411-460
Isotyp:
IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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