PCSK9 rabbit pAb
Produktgrößen
50UL
£ POA
ES20358-50UL
100UL
£ POA
ES20358-100UL
Über dieses Produkt
- SKU:
- ES20358
- Zusätzliche Namen:
- Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-;Neural apoptosis-regulated convertase 1;NARC-1;Proprotein convertase 9;PC9;Subtilisin/kexin-like protease PC9)
- Anwendung:
- Western Blot, Immunohistochemistry
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- cofactor:Calcium.;disease:Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.;enzyme regulation:Inhibited by EGTA.;function:May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.;PTM:The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum; resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.;similarity:Belongs to the peptidase S8 family.;similarity:Contains 1 peptidase S8 domain.;subunit:The precursor protein but not the mature protein may form multimers.;tissue specificity:Expressed in neuro-epithelioma; colon carcinoma; hepatic and pancreatic cell lines; and in Schwann cells.;
- Immunogen:
- Synthesized peptide derived from human PCSK9
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
