TOP2A (Phospho Ser1213) rabbit pAb
Produktgrößen
50UL
£ POA
ES20165-50UL
100UL
£ POA
ES20165-100UL
Über dieses Produkt
- SKU:
- ES20165
- Zusätzliche Namen:
- DNA topoisomerase 2-alpha (EC 5.99.1.3;DNA topoisomerase II; alpha isozyme)
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP-dependent breakage; passage and rejoining of double-stranded DNA.;enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.;function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.;miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils; whereas prokaryotic enzymes relax only negative supercoils.;PTM:Phosphorylation has no effect on catalytic activity.;similarity:Belongs to the type II topoisomerase family.;subcellular location:Generally located in the nucleoplasm.;subunit:Homodimer. Interacts with COPS5.;
- Immunogen:
- Synthesized peptide derived from human TOP2A (Phospho Ser1213)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody