p21 (Acetyl Lys154) rabbit pAb
Produktgrößen
50UL
£ POA
ES20120-50UL
100UL
£ POA
ES20120-100UL
Über dieses Produkt
- SKU:
- ES20120
- Zusätzliche Namen:
- Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1;Melanoma differentiation-associated protein 6;MDA-6;p21)
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity; preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.;induction:By p53; mezerein (antileukemic compound) and interferon beta.;PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.;similarity:Belongs to the CDI family.;tissue specificity:Expressed in all adult human tissues; with 5-fold lower levels observed in the brain.;
- Immunogen:
- Synthesized peptide derived from human p21 (Acetyl Lys154)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody