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Antikörper

ENTK (light chain; Cleaved-Ile785) rabbit pAb

Produktgrößen
50UL
£ POA
ES19990-50UL
100UL
£ POA
ES19990-100UL
Über dieses Produkt
SKU:
ES19990
Zusätzliche Namen:
Enteropeptidase (EC 3.4.21.9;Enterokinase;Serine protease 7;Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain]
Anwendung:
Western Blot, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond.;disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.;function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin; chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen; procarboxypeptidases; and proelastases.;PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease.;similarity:Belongs to the peptidase S1 family.;similarity:Contains 1 MAM domain.;similarity:Contains 1 peptidase S1 domain.;similarity:Contains 1 SEA domain.;similarity:Contains 1 SRCR domain.;similarity:Contains 2 CUB domains.;similarity:Contains 2 LDL-receptor class A domains.;subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond.;tissue specificity:Intestinal brush border.;
Immunogen:
Synthesized peptide derived from human ENTK (light chain; Cleaved-Ile785)
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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