FA9 (light chain; Cleaved-Tyr47) rabbit pAb
Produktgrößen
50UL
£ POA
ES19964-50UL
100UL
£ POA
ES19964-100UL
Über dieses Produkt
- SKU:
- ES19964
- Zusätzliche Namen:
- Coagulation factor IX (EC 3.4.21.22;Christmas factor;Plasma thromboplastin component;PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa; which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions; membrane phospholipids; and factor VIII. Alterations of this gene; including point mutations; insertions and deletions; cause factor IX deficiency; which is a recessive X-linked disorder; also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq; Sep 2015];
- Immunogen:
- Synthesized peptide derived from human FA9 (light chain; Cleaved-Tyr47)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody