Caspase-10 p23/17 (Cleaved-D415) rabbit pAb
Produktgrößen
50UL
£ POA
ES19953-50UL
100UL
£ POA
ES19953-100UL
Über dieses Produkt
- SKU:
- ES19953
- Zusätzliche Namen:
- Caspase-10 (CASP-10;EC 3.4.22.63;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
- Anwendung:
- Western Blot, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7; and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome; non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq; Apr 2011];
- Immunogen:
- Synthesized peptide derived from human Caspase-10 p23/17 (Cleaved-D415)
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Rat, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody