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Antikörper

CAS rabbit pAb

Produktgrößen
50UL
£ POA
ES1844-50UL
100UL
£ POA
ES1844-100UL
Über dieses Produkt
SKU:
ES1844
Zusätzliche Namen:
CSE1L; CAS; XPO2; Exportin-2; Exp2; Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter
Anwendung:
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence, ELISA
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS; while importin-beta mediates translocation through the nuclear pore complex. After translocation; RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm; leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha; and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition; the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq; Jan 2012];
Immunogen:
The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
Isotyp:
IgG
Reaktivitäten:
Human, Rat, Mouse
Versandbedingungen:
Blue Ice
Quelle:
Rabbit
Lagerbedingungen:
-20[o]C
Hersteller:
ELK Biotechnology
Typ:
Antibodies: Polyclonal Antibody
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