BRSK1 rabbit pAb
Produktgrößen
50UL
£ POA
ES1795-50UL
100UL
£ POA
ES1795-100UL
Über dieses Produkt
- SKU:
- ES1795
- Zusätzliche Namen:
- BRSK1; KIAA1811; SAD1; SADB; Serine/threonine-protein kinase BRSK1; Brain-selective kinase 1; Brain-specific serine/threonine-protein kinase 1; BR serine/threonine-protein kinase 1; Serine/threonine-protein kinase SAD-B; Synapses of Amphids
- Anwendung:
- Western Blot, Immunofluorescence, ELISA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;cofactor:Magnesium.;enzyme regulation:Activated by phosphorylation on Thr-205 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.;function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties; possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced; but not IR-induced; DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.;similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.;similarity:Contains 1 protein kinase domain.;similarity:Contains 1 UBA domain.;subcellular location:Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.;tissue specificity:Widely expressed; with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human BRSK1. AA range:361-410
- Isotyp:
- IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Quelle:
- Rabbit
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- ELK Biotechnology
- Typ:
- Antibodies: Polyclonal Antibody
